All statistics for Create Response Surface Design (Box-Behnken)

Find definitions and interpretation guidance for every statistic that is provided with the creation of a response surface Box-Behnken design.

Factors

The number shows how many factors are in the design.

Interpretation

The factors are the variables that you control in the experiment. Factors are also known as independent variables, explanatory variables, and predictor variables. Factors assume only a limited number of possible values, known as factor levels. Factors can have text or numeric levels. For numeric factors, you select specific levels for the experiment, even though many values for the factor are possible.

For example, a chemist is studying how to maximize crystal growth. The chemist wants to study three continuous variables (time, temperature, and percentage of the catalyst in the air inside the chamber) and one categorical factor (additive).

In a response surface design, you designate a low level and a high level for each continuous factor. For a Box-Behnken design, the factor levels are the lowest and highest points in the design.

Base and total runs

The number of base runs is the number of factor level combinations in the base design. The total number of runs is the number of base runs times the number of replicates.

Interpretation

Use the number of base runs to identify the design. Use the number of total runs to verify that the experiment is the right size for your resources. A run is an experimental condition or factor level combination at which responses are measured. Each run corresponds to a row in the worksheet and results in one or more response measurements, or observations. For example, when you create a full factorial design with two factors each with two levels, your experiment has four runs:
Run Factor 1 Factor 2 Response
1 −1 −1 11
2 1 −1 12
3 −1 1 10
4 1 1 9
Note

When you conduct an experiment, the run order should be randomized.

Each run corresponds to a design point, and the entire set of runs is the design. Multiple executions of the same experimental conditions are considered separate runs and are called replicates.

Base and total blocks

Blocks are a group of homogenous experimental units (observations). Base blocks are the number of blocks before replicates are added to the design. Total blocks include any blocks created by replicates in your design.

Although every observation should be taken under identical experimental conditions (other than those that are being varied as part of the experiment), this is not always possible. Nuisance factors that can be classified can be eliminated using a blocked design. For example, an experiment may be carried out over several days with large variations in temperature and humidity, or data may be collected in different plants, or by different technicians. Observations collected under the same experimental conditions are said to be in the same block.

Replicates

The number shows how many replicates are in the design.

Interpretation

Replicates are multiple experimental runs with the same factor level settings (levels). One replicate is equivalent to the base design, where you conduct each factor level combination once. With two replicates, you perform each factor level combination in the base design twice (in random order), and so on.

For example, if you have 3 factors with 2 levels each and you test all combinations of factor levels (full factorial design), the base design represents 1 replicate and has 8 runs (23). If you add 2 replicates, the design includes 3 replicates and has 24 runs.

When planning your experiment, consider the following when you decide whether to add replicates:
  • If you are trying to create a prediction model, multiple replicates can increase the precision of your model.
  • If you include replicates, you might be able to detect smaller effects or have greater power to detect an effect of fixed size.
  • Screening designs (2-level factorial designs), which are used to reduce a large set of factors, usually don't include replicates.
  • Your resources can dictate the number of replicates you can run. For example, if your experiment is extremely costly, you might be able to run the base design only one time.

For information on the difference between replicates and repeats, go to Replicates and repeats in designed experiments.

Design table

The design table shows the factor settings for each experimental run. Because the design table takes up less space than the worksheet, it can be useful for reports with limited space.

The letters at the top of the columns represent the factors and follow the order that you used when you created the design. For continuous factors, the factor settings for each run are displayed in coded units, and Minitab represents the settings as follows:
  • −1 indicates the low factor level
  • 1 indicates the high level
  • 0 indicates the middle point between the low and high level

For categorical factors, Minitab represents the factor settings with numbers that correspond to the categories.

Interpretation

Use the design table to see the factor settings for each run and the order of the runs in the design. In these results, the design table shows 45 runs. In the first run, the continuous factors A and B are at the low setting, continuous factor C is at middle setting, and categorical factor D is at setting 2.

Design Table (randomized)

RunBlkABCD
11-1-102
210-112
310-1-12
410003
51-10-13
61-10-12
7110-12
810113
910002
1010001
1110-1-13
1210003
13101-13
1410-1-11
151-1012
16110-11
1710001
1811101
1910002
201-1101
211-10-11
2210-113
2310111
2410112
251-1102
2611103
27110-13
28101-11
2910-111
3011013
3110001
3210003
331-1-103
341-1011
351-1-101
3610002
3711012
3811102
391-1103
4011-102
41101-12
421-1013
4311-103
4411-101
4511011