The design, or layout, provides the specifications for each experimental run. It includes the blocking scheme, randomization, replication, and factor level combinations. When doing the experiment, you measure the response or responses at the predetermined settings of the experimental conditions. Each experimental condition that is employed to obtain a response measurement is a run.
Minitab provides 2-level full and fractional factorial designs, 2-level split-plot designs, Plackett-Burman designs, and general full factorial designs with more than two levels. When choosing a design you need to: