Select the analysis options for Power and Sample Size for 2x2 Crossover Design Equivalence Test

Stat > Power and Sample Size > Equivalence Tests > 2x2 Crossover Design > Options
Risk level of claiming equivalence when it is not true (alpha)

Specify the risk level (denoted as α or alpha) for the test. Usually, an α of 0.05 works well. An α of 0.05 indicates a 5% risk of rejecting the null hypothesis when it is actually true (type I error).

The value of α is often set by industry guidelines. If you use a smaller value for α, such as 0.01, you can reduce the risk of a type I error. For example, if you perform an equivalence test using the default hypotheses, using a smaller alpha reduces the risk of claiming equivalence when it is not actually true. However, a smaller α also increases the risk that the test is overly conservative and does not allow you to claim equivalence when it is actually true.

The α value also sets the confidence level for the confidence interval. By default, the confidence level is (1 – α) × 100%. For example, if α is 0.05, Minitab calculates a 95% confidence interval.

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