Use Bootstrapping for 2-sample means to explore the sampling distribution of the difference between two population means of two independent groups and to estimate a confidence interval for the difference. You can also use Bootstrapping for 2-sample means to illustrate important statistical concepts. For observations to be independent, the value of a particular observation does not depend on any previous observation. If your observations are not independent, your results may not be valid. For more information, go to How are dependent and independent samples different?.
For more detail on bootstrapping and resampling techniques, go to What is bootstrapping?
To determine whether the population means of two independent groups differ, use Randomization test for 2-sample means.