Stomach acid data

A quality engineer at a consumer healthcare company wants to determine whether their generic antacid is equivalent to a name-brand antacid. Two groups of participants receive a 5-day course of one antacid, followed by a 2-week washout period, and then a 5-day course of the other antacid. Group 1 receives the generic antacid (the test treatment) followed by the name-brand antacid (the reference treatment). Group 2 receives the name-brand antacid followed by the generic antacid. The engineer measures the gastric pH on the last day of each treatment. Because lower pH values are more acidic, higher values mean the drug is more effective. The engineer will consider the antacids equivalent if the test pH is within 10% of the reference pH.

You can use this data to demonstrate Equivalence Test for a 2x2 Crossover Design.